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Dionysios Douroumis

Professor Dionysios Douroumis PGCert, PhD

Professor in Pharmaceutical Technology and Process Engineering; Director of Centre for Research Innovation (CRI)

Key details

Professor Dionysios Douroumis

Professor in Pharmaceutical Technology and Process Engineering; Director of Centre for Research Innovation (CRI)

Professor Dennis Douroumis obtained his BSc in Chemistry and PhD from the Department of Pharmacy at Patras University in Greece. He worked as a postdoctoral fellow (2004) at the Friedrich鈥揝chiller University of Jena, Department of Pharmacy for the development of parenteral formulations of antiepileptic drugs (Novartis Pharma, Basel). He also worked as a team leader (2005) in the development of nano-liposomal formulations and treatment of rheumatoid arthritis by applying photodynamic therapy (Biolitec Pharma GmbH.) Following this, he worked for Phoqus Pharmaceutical plc as a senior scientist at the product development department.

His research area focuses on the development of secondary continuous manufacturing by using hot melt extrusion (HME) of extrusion granulation coupled with PAT tools. His group is also involved in development of targeted anticancer drug delivery systems such as SLNs or NLCs produced by high-pressure homogenization. Finally he is actively involved in ink jetting and 3D printing technologies for the development of medical devices (e.g. microneedles, stents) and personalized medicines.

He has published more than 80 research articles, 7 book chapters and edited two books on HME and the delivery of water insoluble APIs. He has patented two proprietary technologies on the coating of transdermal microneedles and printing of drug eluting stents. Professor Douroumis has delivered keynote presentations at national and international conferences while his group presented several poster presentations.

Pharmaceutical science Science

Chemistry

Responsibilities within the university

Course participation

  • Drug Design and Delivery
  • Pharmaceutical Product Development, Manufacture and Control

Research group

  • Dr Nikolaos Scoutaris (Research Associate)
  • Dr Mary Malamatary (Research Associate)
  • Steven Ross
  • Tumpa Dey
  • Md Sadeque Mithu
  • Jaya Chakraborty
  • Parastou Emami
  • Chris Pissinato
  • Syed Haque

Previous Members

  • Dr Mohammed Maniruzzaman
  • Dr Katarzina Migalska
  • Dr Olga Labovitiadi
  • Dr Ichioma Onyesom
  • Dr Md Jasim Uddin
  • Dr Kapil Kumar Vithani
  • Dr Hiren Moradiya
  • Dr Tariq Islam
  • Dr Mushfiq Akanda
  • Alberto Azor Lafarga

Recognition

Memberships of editorial boards and associations

  • Editor in "Advances in Pharmaceutical Technology", , UK
  • Journal of Nanomedicine and Nanotechnology
  • Pharmaceutica Analytica Acta
  • Pharmaceutical Regulatory Affairs
  • E-Journal of Chemistry
  • International Journal of Nano Studies & Technology
  • The Higher Education Academy (UK)
  • Greek Chemists Association (Greece).

Research / Scholarly interests

Continuous manufacturing via hot melt extrusion (HME)

  • Development of solid dosage forms via continuous HME processing and Process Analytical Tools (PAT) https://www.interreg2seas.eu/fr/imode

Medical devices

  • Drug eluting stents for cardiovascular diseases
  • Microneedles for transdermal delivery.

Nanotechnology

  • Development of novel drug delivery systems for cancer imaging and treatment (liposomes, solid lipid nanoparticles, mesoporous silica nanoparticles and conjugated quantum dots).

Consultancy

CIPER undertakes a range of consultancy projects including preformulation, pharmaceutical/nutraceutical feasibility projects and physicochemical characterization

Other

Patents

Method of coating microneedle devices (WO/20110915 ) - 2011.

Key funded projects

  • Innovative MulticOmponent Drug dEsign (IMODE) for enhancing regional strategic advantages in pharmaceutical and biomedical applications. INTERREG IVA "2 Mers Seas Zeeen", 2016, (鈧�880,891)
  • Development of hot melt extruded water insoluble drugs by using co-processed excipients (Fuji Chemicals, Japan, 拢60,000)
  • Advanced materials and Pharmaceutical Technologies (AMPTEC), INTERREG IVA "2 Mers Seas Zeeen", 2013, (鈧�104,000)
  • Development of a multifunctional stent. (MultiDES). A European project in collaboration with Universities of Lille 1 and Lille 2 (France) funded by INTERREG IVA "2 Mers Seas Zeeen", 2010, (鈧�892,000)

Recent publications

Article

Kolipaka, Siva Satyanarayana , Junqueira, Laura Andrade, Ross, Steven, Garg, Vivek , Mithu, Md Sadeque Hossain , Bhatt, Saumil , Douroumis, Dionysios (2024), . Springer. In: , , , . Springer, AAPS PharmSci Tech, 25: 174 1530-9932 (Online) (doi: https://doi.org/10.1208/s12249-024-02890-y).

Boateng, Joshua , Hafezi, Forough, Tabriz, Atabak, Douroumis, Dionysios (2023), . Elsevier. In: , , , . Elsevier, Journal of Drug Delivery Science and Technology, 86: 104684 . pp. 1-13 ISSN: 1773-2247 (Print), 2588-8943 (Online) (doi: https://doi.org/10.1016/j.jddst.2023.104684).

Ghanizadeh Tabriz, Atabak , Gonot-Munck, Quentin, Baudoux, Arnaud, Garg, Vivek , Farnish, Richard , L.Katsamenis, Orestis , Hui, Ho-Wah , Boersen, Nathan , Roberts, Sandra , Jones, John (2023), . MDPI. In: , , , . MDPI, Pharmaceutics, 15: 2230 (9) . pp. 1-19 1999-4923 (Online) (doi: https://doi.org/10.3390/pharmaceutics15092230).

Akanda, Mushfiq , Mithu, Md Sadeque Hossain, Douroumis, Dionysios (Dennis) (2023), . Elsevier. In: , , , . Elsevier, Journal of Drug Delivery Science and Technology, 86: 104709 . pp. 1-14 ISSN: 1773-2247 (Print), 2588-8943 (Online) (doi: https://doi.org/10.1016/j.jddst.2023.104709).

Tabriz, Atabak Ghanizadeh , Kuofie, Hannah, Scoble, James, Boulton, Sam , Douroumis, Dionysios (Dennis) (2023), . Elsevier. In: , , , . Elsevier, Journal of Drug Delivery Science and Technology, 86: 104699 . pp. 1-13 ISSN: 1773-2247 (Print), 2588-8943 (Online) (doi: https://doi.org/10.1016/j.jddst.2023.104699).

Ghanizadeh Tabriz, Atabak , Viegas, Beatriz, Okereke, Michael, Uddin, Md Jasim , Arribas Lopez, Elena , Zand Fard, Nazanin , Ranatunga, Medhavi , Getti, Giulia , Douroumis, Dionysios (2022), . MDPI. In: , , , . MDPI, Micromachines, 13: 1368 . pp. 1-16 2072-666X (Online) (doi: https://doi.org/10.3390/mi13091368).

Junqueira, Laura Andrade , Ghanizadeh Tabriz, Atabak, Raposo, Francisco Jos茅, Carobini, Luana Rocha , Vaz, Urias Pard贸cimo , Brand茫o, Marcos Ant么nio Fernandes , Douroumis, Dionysios , Raposo, N谩dia Rezende Barbosa (2022), . MDPI. In: , , , . MDPI, Pharmaceutics, 14: 159 (1) 1999-4923 (Online) (doi: https://doi.org/10.3390/pharmaceutics14010159).

Mohamdeen, Youssra Moustafa Gadelkareem , Tabriz, Atabak Ghanizadeh, Tighsazzadeh, Mohammad, Nandi, Uttom , Khalaj, Roxanne , Andreadis, Ioannis , Boateng, Joshua , Douroumis, Dionysios (2021), . Oxford University Press - Royal Pharmaceutical Society of Great Britain. In: , , , . Oxford University Press - Royal Pharmaceutical Society of Great Britain, Journal of Pharmacy and Pharmacology, 74: rgab173 (10) . pp. 1467-1476 ISSN: 0022-3573 (Print), 2042-7158 (Online) (doi: https://doi.org/10.1093/jpp/rgab173) NB Item availability restricted.

Economidou, Sophia N. and , Douroumis, Dionysios (2021), . Elsevier. In: , , , . Elsevier, Advanced Drug Delivery Reviews, 173 . pp. 60-69 ISSN: 0169-409X (Print), 1872-8294 (Online) (doi: https://doi.org/10.1016/j.addr.2021.03.007).

Akanda, Md Mushfiq , Getti, Giulia, Nandi, Uttom, Mithu, Md Sadeque Hossain , Douroumis, Dionysios (2021), . Elsevier. In: , , , . Elsevier, International Journal of Pharmaceutics, 599: 120416 ISSN: 0378-5173 (Print), (doi: https://doi.org/10.1016/j.ijpharm.2021.120416).

Akanda, Mushfiq , Getti, Giulia, Nandi, Uttom, Sadeque Mithu, Md , Douroumis, Dionysios (2021), . Elsevier. In: , , , . Elsevier, International Journal of Pharmaceutics, 599: 120416 ISSN: 0378-5173 (Print), (doi: https://doi.org/10.1016/j.ijpharm.2021.120416).

Economidou, Sophia , Pissinato Pere, Cristiane, Okereke, Michael, Douroumis, Dionysios (2021), . MDPI AG. In: , , , . MDPI AG, Micromachines, 12 (2) ISSN: 2072-666X (Print), (doi: https://doi.org/10.3390/mi12020117).

Economidou, Sophia N. , Uddin, Md. Jasim, Marques, Manuel J., Douroumis, Dennis , Ting Sow, Wan , Li, Huaqiong , Reid, Andrew , Windmill, James F.C. , Podoleanu, Adrian (2020), . Elsevier. In: , , , . Elsevier, Additive Manufacturing, 38: 101815 ISSN: 2214-7810 (Print), 2214-8604 (Online) (doi: https://doi.org/10.1016/j.addma.2020.101815).

Ghanizadeh Tabriz, Atabak , Nandi, Uttom, Hurt, Andrew, Hui, Ho-Wah , Karki, Shyam , Gong, Yuchuan , Kumar, Sumit , Douroumis, Dionysios (2020), . Elsevier. In: , , , . Elsevier, International Journal of Pharmaceutics, 593: 120147 ISSN: 0378-5173 (Print), (doi: https://doi.org/10.1016/j.ijpharm.2020.120147).

Nandi, Uttom , Trivedi, Vivek, Douroumis, Dennis, Mendham, Andrew P. , Coleman, Nichola J. (2020), . MDPI. In: , , , . MDPI, Pharmaceuticals, 13: 182 (8) 1424-8247 (Online) (doi: https://doi.org/10.3390/ph13080182).

Hafezi, Forough , Shorter, Susan, Tabriz, Atabak Ghanizadeh, Hurt, Andrew P. , Elmes, Victoria , Boateng, Joshua , Douroumis, Dionysios (2020), . MDPI. In: , , , . MDPI, Pharmaceutics, 12: 550 (6) ISSN: 1999-4923 (Print), 1999-4923 (Online) (doi: https://doi.org/10.3390/pharmaceutics12060550).

Mithu, Sadeque Hossain , Ross, Steven A., Alexander, Bruce D., Douroumis, Dennis (2019), . Royal Society of Chemistry. In: , , , . Royal Society of Chemistry, Green Chemistry, 22 (2) . pp. 540-549 ISSN: 1463-9262 (Print), 1463-9270 (Online) (doi: https://doi.org/10.1039/C9GC03528A).

Uddi, Md Jasim , Scoutaris, Nikolaos, Economidou, Sophia N., Giraud, Clementine , Chowdhry, Babur , Donnelly, Ryan F. , Douroumis, Dennis (2019), . Elsevier. In: , , , . Elsevier, Materials Science and Engineering: C, 107: 110248 ISSN: 0928-4931 (Print), 1873-0191 (Online) (doi: https://doi.org/10.1016/j.msec.2019.110248) NB Item availability restricted.

Economidou, Sophia N. , Pissinato Pere, Cristiane Patricia, Reid, Andrew, Uddin, Jasim Md. , Windmill, James F.C. , Lamprou, Dimitrios A. , Douroumis, Dennis (2019), . Elsevier. In: , , , . Elsevier, Materials Science and Engineering C, 102 . pp. 743-755 ISSN: 0928-4931 (Print), (doi: https://doi.org/10.1016/j.msec.2019.04.063).

Boateng, Joshua , Hafezi, Forough, Scoutaris, Nikolaos, Douroumis, Dennis (2019), . Elsevier B.V.. In: , , , . Elsevier B.V., International Journal of Pharmaceutics, 560 . pp. 406-415 ISSN: 0378-5173 (Print), 1873-3476 (Online) (doi: https://doi.org/10.1016/j.ijpharm.2019.02.020).

Loughrill, Emma , Thompson, Sharon, Owusu-Ware, Samuel K., Snowden, Martin J. , Douroumis, Dennis , Zand Fard, Nazanin (2019), . Elsevier. In: , , , . Elsevier, Food Chemistry, 286 . pp. 368-375 ISSN: 0308-8146 (Print), (doi: https://doi.org/10.1016/j.foodchem.2019.01.121).

Ross, Steven A. , Ward, Adam, Basford, Pat, McAllister, Mark , Douroumis, Dennis (2018), . American Chemical Society (ACS). In: , , , . American Chemical Society (ACS), Crystal Growth & Design, 19 (2) . pp. 876-888 ISSN: 1528-7483 (Print), 1528-7505 (Online) (doi: https://doi.org/10.1021/acs.cgd.8b01440).

Pere, Cristiane Patricia Pissinato , Economidou, Sophia N., Lall, Gurprit, Ziraud, Cl茅mentine , Boateng, Joshua , Alexander, Bruce D. , Lamprou, Dimitrios A. , Douroumis, Dennis (2018), . Elsevier. In: , , , . Elsevier, International Journal of Pharmaceutics, 544 (2) . pp. 425-432 ISSN: 0378-5173 (Print), 1873-3476 (Online) (doi: https://doi.org/10.1016/j.ijpharm.2018.03.031).

Scoutaris, Nikolaos , Ross, Steven A., Douroumis, Dennis (2018), . Springer Verlag. In: , , , . Springer Verlag, Pharmaceutical Research, 35 ISSN: 0724-8741 (Print), 1573-904X (Online) (doi: ).

Scoutaris, Nicolaos , Malamatari, Maria, Letellier, Adrien, Douroumis, Dennis (2017), . Springer US. In: , , , . Springer US, Drug Delivery and Translational Research, 8 (1) . pp. 32-42 ISSN: 2190-393X (Print), 2190-3948 (Online) (doi: https://doi.org/10.1007/s13346-017-0430-3).

Maniruzzaman, Mohammed , Ross, Steven A., Dey, Tumpa, Nair, Arun , Snowden, Martin J. , Douroumis, Dennis (2017), . Elsevier B.V.. In: , , , . Elsevier B.V., International Journal of Pharmaceutics, 526 (1-2) . pp. 496-505 ISSN: 0378-5173 (Print), (doi: https://doi.org/10.1016/j.ijpharm.2017.05.020) NB Item availability restricted.

Maniruzzaman, M. , Ross, S.A., Islam, M.T, Scoutaris, N. , Nair, A. , Douroumis, Dennis (2017), . Taylor & Francis. In: , , , . Taylor & Francis, Drug Development and Industrial Pharmacy, 43 (6) . pp. 947-957 ISSN: 0363-9045 (Print), 1520-5762 (Online) (doi: https://doi.org/10.1080/03639045.2017.1287716) NB Item availability restricted.

Maniruzzaman, Mohammed , Farias, Smirna, Slipper, Ian J., Boateng, Joshua S. , Chowdhry, Babur Z. , Nair, Arun , Douroumis, Dennis (2016), . Wiley. In: , , , . Wiley, Journal of Pharmacy and Pharmacology, 68 (7) . pp. 890-900 ISSN: 0022-3573 (Print), 2042-7158 (Online) (doi: http://doi.org/10.1111/jphp.12569) NB Item availability restricted.

Scoutaris, Nikolaos , Chai, Feng, Blandine, Maurel, Sobocinski, Jonathan , Zhao, Min , Moffat, Jonathan G. , Craig, Duncan Q. , Martel, Bernard , Blanchemain, Nicolas , Douroumis, Dennis (2016), . American Chemical Society. In: , , , . American Chemical Society, Molecular Pharmaceutics, 13 (1) . pp. 125-133 ISSN: 1543-8384 (Print), 1543-8392 (Online) (doi: http://dx.doi.org/10.1021/acs.molpharmaceut.5b00570).

Book section

Tabriz, Atabak Ghanizadeh , Douroumis, Dennis, Boateng, Joshua (2019), . Wiley. In: , , In: Joshua Boateng (ed.), Therapeutic Dressings and Wound Healing Applications. Wiley, (1st) . pp. 385-398 . ISBN: 9781119433262 (doi: https://www.wiley.com/en-gb/Therapeutic+Dressings+and+Wound+Healing+Applications-p-9781119433262).

Patent

Douroumis, Dionysios , Bradley, Michael, Scoutaris, Nikolaos (2017), . In: , , , . , (doi: ).